1742-1743 / 2063
Head & neck
•
Head & neck reirradiation:
selection criteria
–
Patient
related considerations
•
No severe sequelae of previous radiation treatment
•
No significant comorbidities
•
PET-CT is suggested for staging
•
Interval between RT courses: at least 6 months, preferably longer
(1y)
•
Better prognosis:
–
Previous surgery
–
Small (<30cm³) tumor size; caution with bulky tumors (>60cm³)
–
True second primary tumors (as compared to recurrences)
–
Tumors in nasopharynx and larynx
–
EGFR expression/HPV status: uncertain (needs to be evaluated in the
context of re-irradiation)
Cacicedo Cancer Treatment Reviews 2014