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Head & neck

Risk of late damage

is higher in retreated

patients…

But cumulative total

dose for 20%

complication rate at 5 y

is higher than predicted

from single course

treatment

(EQD2

3

= 86 vs 67 Gy)

indicating

partial

recovery!

Complication free survival (%)

0

2

4

6

8

10

0

20

40

60

80

100

Time from (re)irradiation (years)

Reirradiation

N = 487

Single course

N = 3635

Lee AWM et al. Int J Radiat Oncol Biol Phys 20000