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Modified from Stewart FA &
van der Kogel AJ
Semin
Radiat Oncol
1994
0 20 40 60 80 100 120
0 20 40 60 80 100
0
20
40
60
80
100
0
20
40
60
80
100
120
Initial dose (% of EQD
tol
)
Reirradiation dose (% of EQD
tol
)
skin/oral mucosa
lung
pneumonitis
spinal cord
kidney
(bladder)
(heart?)
early effects
late effects
Summary experimental data
Several, but not all, normal tissues are able to
tolerate considerable retreatment with radiation