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Kidney

Retreatment tolerance mouse kidney

Stewart Int J Radiat Oncol Biol Phys 1989

No recovery between 1

day and 6 months after

initial treatment

Progression of

(subclinical) damage

Retreatment tolerance

decreases with time

Extreme caution when

re-irradiating kidneys!

Reirradiation dose (Gy)

0 2 4 6 8 10 12 14 16

Reduced kidney function

0

2

4

6

8

10

12

14

treatment alone

6.5 mo

post 6 Gy

2 wks

post

6 Gy