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Kidney
•
Retreatment tolerance mouse kidney
Stewart Int J Radiat Oncol Biol Phys 1989
No recovery between 1
day and 6 months after
initial treatment
Progression of
(subclinical) damage
Retreatment tolerance
decreases with time
Extreme caution when
re-irradiating kidneys!
Reirradiation dose (Gy)
0 2 4 6 8 10 12 14 16
Reduced kidney function
0
2
4
6
8
10
12
14
treatment alone
6.5 mo
post 6 Gy
2 wks
post
6 Gy