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ESTRO

2017

Image-Guided Radiation Therapy in HNSCC

0

50

100

150

200

GTV

CTV

PTV

Average (± sem) volume (cc)

CT-scan

FDG-PET

Larynx/hypopharynx (n=9)

ANOVA: p<0.05

0

50

100

150

200

250

GTV

CTV

PTV

CT-scan

FDG-PET

ANOVA: p<0.01

Oropharynx (n=10)

Average (± sem) volume (cc)

Impact of imaging modality on CTV/PTV delineation

Geets

et al

, 2003

ESTRO

2017

Impact of imaging modality on dose distribution

Image-Guided Radiation Therapy in HNSCC

CT-based target volume

FDG PET-based target volume