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ESTRO
2017
Validation study in locally advanced HNSCC
•
GTV-T
FDG-PET
< GTV-T
CT
•
CTV-T
FDG-PET
< CTV-T
CT
•
PTV-T
FDG-PET
< PTV-T
CT
(oropharyngeal SCC)
•
More parotid sparing with the use of FDG-PET (oropharyngeal SCC)
•
Loco-regional control probability within the expected range
Use of FDG-PET for target volume delineation in 3D-
CRT/IMRT for head and neck tumors
Grégoire & Leclerc, 2013
ESTRO
2017
•
Local relapse: 9/41
- No marginal recurrence (i.e. in the CTV
CT
and not CTV
PET
)
•
Regional relapse: 2/41
•
Metastasis: 6/41
•
Second primary: 2/41
Validation study in locally advanced HNSCC
Grégoire & Leclerc, 2013