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ESTRO

2017

Validation study in locally advanced HNSCC

GTV-T

FDG-PET

< GTV-T

CT

CTV-T

FDG-PET

< CTV-T

CT

PTV-T

FDG-PET

< PTV-T

CT

(oropharyngeal SCC)

More parotid sparing with the use of FDG-PET (oropharyngeal SCC)

Loco-regional control probability within the expected range

Use of FDG-PET for target volume delineation in 3D-

CRT/IMRT for head and neck tumors

Grégoire & Leclerc, 2013

ESTRO

2017

Local relapse: 9/41

- No marginal recurrence (i.e. in the CTV

CT

and not CTV

PET

)

Regional relapse: 2/41

Metastasis: 6/41

Second primary: 2/41

Validation study in locally advanced HNSCC

Grégoire & Leclerc, 2013