244-245 / 2063
carcinoma cells
(Chu, Dewey et al, 2004)
p21-/-:
⬇
G1 arrest
⬆
survival
p21-/-
14-3-3σ-/-:
⬇
late S/G2 arrest
⬇
survival
14-3-3σ-/-
• The type of cell death has no
relation with sensitivity
• Death and removal of cells after
irradiation may take many days or
even weeks