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ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr

EORTC 22851 - Mucositis Gr. 3+4

0

2

4

6

8

10

12

14

AF: 72 Gy / 45 F / 5 wk

CF: 70 Gy / 35 F / 7 wk

p=0.011

Gr. 3 mucosal late effects

- deep necrosis

- edema/tracheostomy

Fraction of patients [%]

Effect of overall treatment time

CLE: Consequences

data from: Horiot et al., RTO 44, 1997, 111-121