424-425 / 2063
ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr
Take home message II
Late effects:
•
all tissues
•
complex pathogenesis
(parenchyma, fibroblasts, endothelium, macrophages)
•
irreversible (?)
•
dose-dependent latency
•
dose-dependent progression rate
•
incidence (tolerance) ~ follow up