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6
ESTRO
2017
Conventional fractionation
1.8 – 2.0 Gy per fraction, 5 fractions per week
IIIII IIIII IIIII IIIII IIIII IIIII IIIII
none?
none?
³
60
≥ 60
Glioblastoma
Melanoma
Resistant
³
90 (subclinical)
~ 85 (Ø 1 cm)
~ 70 (Ø 3 cm)
~ 30 (Ø 5 cm)
50
60
70
SCC,
Adeno-Ca
Intermediate
³
90
£
45
Seminoma, Lymphoma
Sensitive
Tumor control (%)
Dose
(Gy)
Example
ESTRO
2017
Bataini et al, 1982
,
45
55
65
75
85
95
Total dose (Gy)
0
20
40
60
80
100
120
Tumor control (%)
Dose-response curve for neck nodes ≤ 3 cm
Tumor Control Probability (TCP)