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SVCS treatment recommendations I

• Asses life threatening symptoms:

cerebral or laryngeal oedema (5%),

tracheal obstruction and

pericardial effusion

(Yu 2008 Thorac Oncol, Soufe Intervent Radiol, 2013)

– If yes

:

endovascular stenting (optimal, fast relief), or immediate RT or CHT

– If less severe

:

histology first, staging , MDT.

• SCLC, DLBCL – CHT

and

RT

• NSCLC and other – stenting

and

RT

• RT vs CHT similar response rate

– For SCLC 76,9% vs 77.6%

– For NSCLC 59% vs 63%

JK 19/49