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Radiotherapy for SVCS I

RT schedules

: fractions 3-4 Gy.

• SVCS in lung cancers is

dose dependent

, dose should be above 20Gy!

– 10 x 3 Gy,

– 5 x 4 Gy,

• Improvement ~ 72h

• Symptoms - 77% response but only 11% of full recanalisation and 24%-

partial in imaging

• Why such discrepancy?

– RT decrease tumor size what allows for better collateral circulation

(Wilson NEJM 2007)

JK 21/49