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Breast re-irradiaton

• Role unclear – individual

decisions in reurrence in skin,

ribs, subcutaneous tissue,

limiting factor: doses for lungs

and heart

• EBRT : Combined dose to 100

Gy for local control

(Wurschmidt F

Radiat Oncol 2008, Harkenrider M Clin

Breast Cancer 2011)

• BT:

(Harms W IJROBP 2001)

• Hypertermia enhaces effect of

RT 41 vs 59% of CR

(Koulalais V,

Clin Cance Res 2002)

Before and 7 mts after BT: 5 x 6 Gy

Wu N, JCB 2015

JK 26/49