Breast re-irradiaton
• Role unclear – individual
decisions in reurrence in skin,
ribs, subcutaneous tissue,
limiting factor: doses for lungs
and heart
• EBRT : Combined dose to 100
Gy for local control
(Wurschmidt F
Radiat Oncol 2008, Harkenrider M Clin
Breast Cancer 2011)
• BT:
(Harms W IJROBP 2001)
• Hypertermia enhaces effect of
RT 41 vs 59% of CR
(Koulalais V,
Clin Cance Res 2002)
Before and 7 mts after BT: 5 x 6 Gy
Wu N, JCB 2015
JK 26/49