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Liver SBRT guidelines and toxicity

• Generally, doses 30-60 Gy in 1-6 fraction, tumor size about 6 cm, not more

than 5 mets

• RILD –rare, transient elevation liver ezymes

• No more than 700 cc uninvolved liver received 15 Gy in 3 fraction

(QUANTEC)

(Pan CC IJROBP 2010)

• Rib fracture, subcutaneous tissue damage, duodenal ulceration –very rare

JK 37/49