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A Practical Example: SRT Case

Intracranial lesion: 3 x 8 Gy @ 80%

SD of the penumbra is 3.2 mm

E2E test device error (1 SD) = 0.4 mm (measured over a long period)

Localization (delineation) error = 1.0 mm (1 SD)

Systematic error = 0.5 mm (1 SD) [measured from 30-fraction treatments]

Random error = 0.5 mm (1 SD) [measured from 30-fraction treatments]

Intra-fraction error = 0.5 mm ( 1 SD) [measured from 30-fraction treatments

at end of treatment]