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A Practical Example: SBRT Lung Case
 T1 primary lung lesion: 3 x 18 Gy @ 80%
 Alignment on time-averaged tumor position by CBCT
 Tumor in lung tissue
 E2E test device error (1 SD) = 0.4 mm (measured over a long period)
 Localization (delineation) error = 2.0 mm (1 SD)
 Systematic error = 1.0 mm (1 SD) [measured from 3-fraction treatments]
 Random error = 1.0 mm (1 SD) [measured from 3-fraction treatments]
 Intra-fraction amplitude = 1 – 25 mm