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A Practical Example: SRT Case
 Intracranial lesion: 3 x 8 Gy @ 80% N=3, β=0.84
 SD of the penumbra is 3.2 mm σpen =3.2 mm
 E2E test device error (Σ) = 0.4 mm Σ1 =0.4 mm
 Localization (delineation) error = 1.0 mm (1 SD) Σ 2=1.0 mm
 Systematic error = 0.5 mm (1 SD) Σ eff=0.58 mm
 Random error = 0.5 mm (1 SD) σeff=0.41 mm
 Intra-fraction error = 0.5 mm ( 1 SD) σeff=0.20 mm