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Radiation damage
Lipide
NAA
Cho
4.0
3.0
2.0
1.0
3.5
2.5
1.5
0.5
ppm
Lipids
NAA
4.0
3.0
2.0
1.0
3.5
2.5
1.5
0.5
ppm
Tumor progression
Enhancing lesion post radiotherapy
MRSI in brain lesions: Summary
Pathology
Cho/Cr Cho/Cho(n) NAA/Cr
Cho
peritumoral
High grade glioma
⇑⇑
⇑⇑
⇓ ⇓
⇑
Low grade glioma
⇑
⇑
⇓
~
Radiation necrosis
⇓
⇓
⇓
⇓
Metastasis
⇑
⇑
⇓ ⇓
⇓
Lymphoma
⇑
⇑
⇓ ⇓
⇓
Law 2004
Visions
23
Na Imaging
3 T
7 T
1,5 T
Courtesy of M.A. Weber and M. Bock, Heidelberg
Sodium imaging
•
Possible applications:
–
Viability
–
Therapy monitoring
Positron emission tomography