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Gamma decay
Positron decay
PET isotopes
Isotope
T
1/2
(min)
E
max
(MeV)
11
C
20,4
0,97
13
N
9,9
1,19
15
O
2,05
1,72
18
F
109
0,64
68
Ga
68
1,9
PET tracers - oncology
•
Metabolism
–
18
FDG
•
Amino acids
–
11
C-methionine
–
18
F-tyrosine
–
11
C-AIB
–
18
FET
•
Peptides
–
68
Ga-DOTATOC
–
68
Ga-PSMA
•
Perfusion
–
H
2
15
O
•
Proliferation
–
11
C-thymidine
–
18
FLT
–
18
F-Ethyl Choline
–
11
C-Choline
•
Hypoxia
–
18
F-MISO
•
Drugs
–
18
FU
68Ga-DKFZ-PSMA-11
Eder M et al. Bioconjugate Chem 2012; 23: 688-697.
Afshar-OromiehAet al. Eur J Nucl Med Mol Imaging 2013; 40: 486-495.
FDG metabolism
Vascular
compartment
Extracellular
space
Metabolic compartment
Capillarymembrane
CT/PET hybrid system