PowerPoint Presentation

A Phase II Randomized Trial Comparing Intensity Modulated Radiation Therapy

(IMRT) with Conventional Radiation Therapy in Stage IIB Carcinoma Cervix

(NCT00193804/TMH/158/2004): November 2004

100 patients

Conventional External RT (40 Gy /20#)

+ ICA – HDR (7 Gy x 5#)

with Concomitant Chemo-radiatio

100 patients

IMRT Pelvis (50 Gy/25#)

+ ICA – HDR (7 Gy x 5#)

with Concomitant Chemo-radiation

• IMRT reduces acute and late RT toxicity’s by 15-25%

• Accrual period 5 years, finished

•However, 10 Gy more in IMRT arm

Hypothesis

Randomised trial IMRT versus 3D CRT, TMH