2
Vitamin B
1
, Thiamin
“The first water‐soluble vitamin”
First discovered in 1910 and gave birth to
the term vitamine (
vital amine
) in 1912.
Thiamin was first isolated and characterized
in 1926, and was designated B
1
in 1927.
The name thiamine is derived from thio‐
vitamine meaning the sulfur containing
vitamin.
Vitamin B
1
deficiency
B
1
dependent processes are present in
every cell in your body!
The nervous system is particularly sensitive
to B
1
deficiency due to the importance of
oxidative metabolism
The most common syndromes of B
1
deficiency are beriberi, Wernicke‐Korsakoff,
and optic neuropathy.
