1027 / 1983
EBRO
2017
Diagnostic work-up
M staging: PET-CT
Detection of occult metastases
•
Initial studies using FDG PET:
•
Metastatic disease detected in
15% patients
considered potentially resectable*.
•
Prospective trial 187 patients showed confirmed up-
staging in
18 (9.5%) patients
with unconfirmed
metastases
‡
•
25/156
(16%)
patients up staged to M1b disease on PET-
CT
§
*Flamen, P., A. Lerut, et al. (2000). J Clin Oncol
18
(18): 3202
-10
‡
Meyers, B. F., R. J. Downey, et al. (2007). J Thorac Cardiovasc Surg
133
(3): 738
-45
§
Purandare, N. C., C. S. Pramesh, et al. (2014). Nucl Med Commun
35
(8): 864-869