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Simchoni et al, 2006

Breast T, 82

Breast T, 39

Breast T, 69

Breast T, 48

Breast T, 49

Breast T, 50

73 yrs

Ovary T, 60

Ovary T, 41

Ovary T, 54

Ovary T, 47

Ovary T, 43

46 yrs

Two families with the same BRCA1 mutat ion but with a

different phenotype