1515 / 1983
Main features of the management of women carrying a
BRCA1
or
BRCA2
germline mutation
Annual breast screening with mammography, ultrasonography, and MRI,
beginning at age 30
Prophylactic surgery
•
oophorectomy recommended between at age 40 when
BRCA1
mutation and delayed if
BRCA2
mutation
•
mastectomy is an option which must be discussed at 30 yrs or
latter (but not too late)
Medical prevention (still in clinical trials)
•
Anti-estrogenes such as aromatase inhibitors after menopauses