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Page Background

Prophylactic mastectomy

• The resultant lack of knowledge drives and sustains patient

anxiety, sometimes prompting them to select mastectomy in

hopes of a cure while sacrificing cosmesis, body image, and

perhaps sexuality

Kiebert GM, et al, J Clin Oncol. 1991

Schover

LR.CA

Cancer Journal for Clinicians. 1991

BRCA1/2

mutation carriers who underwent prophylactic

mastectomy reported a less favorable body image, while

70% of them reported changes in their sexual relationships.

Van Oostrom I, et al. Long-term psychological impact of carrying a

BRCA1/2 mutation and prophylactic surgery: a 5-year follow-up study. Journal of

Clinical Oncology.2003