1524 / 1983
BRCA1
No previous
breast T
N = 869
BRCA2
No previous
breast T
N = 501
BRCA1
Previous
breast T
N = 397
BRCA2
Previous
breast T
N =250
Oophorectomy
Breast T
236
32 (13.6%)
100
7 (7.0%)
138
19 (13.8%)
70
4 (5.7%)
No oophorectomy
Breast T
633
129 (20.4%)
401
94 (23.4%)
259
46 (17.8%)
180
14 (7.8%)
Domchek et al, 2010
Protective effect of oophorectomy on the breast cancer risk