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Abbott Nutrition Division

Simultaneous Determination of Total Vitamin B

6,

B

2,

B

3

and B

1

in Infant

Formula Products by LC-MS/MS Using Enzymatic Digestion

Common synonyms include vitamin B

1

, Metatone, Aneurin, Anti-beriberi factor, Biamine,

Betalin S, Betamin, BetaSol, Thiamine and Thiamine Chloride.

The CAS# for Thiamine Chloride Hydrochloride is 59-43-8.

The chemical structure of Thiamine Chloride Hydrochloride is shown below:

f) Niacin

Niacinamide is the physiologically active form of niacin. Niacinamide (nicotinamide) functions

metabolically as a component of the coenzyme nicotinamide adenine dinucleotide (NAD) and

nicotinamide adenine dinucleotide phosphate (NADP). Both NAD and NADP function as proton

donors and acceptors in metabolic processes including glycolysis, fatty acid synthesis, and

respiration.

Naturally occurring nicotinic acid is readily converted

in-vivo

to the biologically active

niacinamide.

The aqueous solution is neutral to litmus. One gram of niacinamide is soluble in about 1 mL of

water and in about 1.5 mL of alcohol.

Niacinamide is the form of niacin present in Abbott Nutrition water-soluble vitamin premixes.

The molecular formula of niacinamide is C

6

H

6

N

2

0 and its molecular weight is 122.12 g/mol.

The CAS# for niacinamide is 98-92-0.

Synonyms include: 3-pyridine carboxylic acid amide, 3-pyridinecarboxamide, nicosan 2, nicota,

nicotamide, nicotililamido, nicotine acid amide, nicotinamide, nicotinic acid amide, nicotinic

amide, nicotol, nicotylamide, nicovit, nicovitol, nicozymin, niko-tamin, Ni-nicotyl, niocinamide,

niozymin, pelmin, pelonin amide, pp-faktor, pyridine-3-carboxylic acid amide, savacotyl, vitamin

B

3

, vitamin PP, witamina pp, amide pp, aminicotin, amixicotyn, amnicotin, austrovit pp, benicot,

N

N

H

3

C

NH

2

N

S

CH

3

OH

HCl

.

Cl

-

24

BVit-02

FOR ERP USE ONLY

DO NOT DISTRIBUTE