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Page Background

Patient reported

subjective symptoms

Patient reported

objective symptoms

Physician assessed

objective symptoms

Analytic outcomes

(lab / imaging)

Morbidity assessment

in clinical trials (Kirchheiner)

Anemia defined as reduction in the amount

of hemoglobin in 100 ml of blood.

Patient reported impact of

symptoms on ADL

Atrophy of the vaginal mucosa,

ulceration, necrosis, fistula

Number of stools / day, consistency of stool

Fatigue, pain, sexual functioning problems

Impact of difficulties controlling bowel on

activities of daily life / quality of life

objective

subjective

clinical decision / medical intervention

Patient reported complex

multidimensional concepts

Health-related quality of life, functioning

aspects in daily life, psychological status