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High Grade Gliomas

Wen et al. J Clin Oncol 2010; 28: 1963-72

Response classification:

Complete remission (CR)

Partial remission (PR)

Stable disease (SD)

Progressive disease (PD)

Post contrast T1W: >10mm

Bidimensional measurement

excluding cystic cavity

PR: >50% decrease in

enhancing lesions;

stable/improved non-

enhancing T2/flair lesions

PD: >25% increase in

enhancing lesions; increase in

non-enhancing T2/flair

lesions; new lesions

RANO criteria