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Chapter 6
Table 6.3
Discrimination training
AUD
VIS
Day
Correct
Mean (SEM)
Incorrect
mean (SEM)
F(1,23)
Correct
Mean(SEM)
Incorrect
mean (SEM)
F(1,23)
1
18.81 (3.07)
18.85 (2.68)
< 1
17.69 (3.02)
20.19 (3.08)
5.429
*
2
29.13 (3.90)
20.10 (2.29)
15.042
***
24.19 (3.20)
24.48 (3.43)
<1
3
28.31 (3.45)
17.17 (2.09)
27.455
***
28.69 (4.41)
26.50 (3.96)
3.372
^
4
40.96 (5.13)
22.85 (2.45)
31.353
***
30.33 (3.17)
29.48 (3.21)
<1
5
44.06 (4.21)
21.54 (2.43)
47.350
***
38.75 (3.37)
34.46 (3.06)
11.607
**
6
45.29 (3.53)
22.44 (2.07)
75.362
***
42.79 (3.68)
35.77 (3.09)
15.027
***
7
56.50 (6.27)
25.98 (3.10)
54.420
***
51.52 (4.59)
44.15 (2.65)
4.347
*
8
58.31 (4.28)
28.90 (3.68)
72.552
***
52.04 (4.25)
40.79 (3.73)
25.108
***
9
65.92 (5.75)
22.10 (2.39)
89.538
***
55.69 (5.78)
40.77 (4.13)
20.971
***
10
68.56 (7.04)
27.52 (2.91)
51.151
***
49.27 (4.85)
37.15 (3.42)
23.008
***
11
66.67 (6.05)
26.60 (2.51)
60.396
***
57.15 (7.47)
36.54 (3.93)
22.899
***
12
67.92 (5.99)
24.35 (2.47)
44.035
***
61.56 (6.01)
40.17 (3.56)
22.500
***
13
75.90 (6.68)
27.23 (3.13)
82.304
***
65.92 (6.75)
49.88 (4.67)
16.281
***
14
82.67 (8.44)
28.81 (3.22)
44.893
***
62.00 (5.95)
39.90 (3.67)
33.093
***
15
78.25 (5.61)
29.77 (2.51)
77.400
***
63.65 (6.01)
39.48 (3.67)
19.949
***
^ = p < 0.1, * = p < 0.05, ** = p < 0.01, *** p < 0.001,
bold = significant after correction for multiple (i.e. 30) t-tests: p < 0.001
We anticipated that all animals, except for those with lesions of the AcbC would show
increased flexibility in the high vs. low reward condition. To assess the role of the AcbC,
we first assessed whether surgery affected rewarded task-switching performance in the sham
and lesion group separately, by comparing performance on pre- and post-surgery sessions.
We anticipated an effect of surgery in the lesion group, but not in the sham group. Next,
we assessed group effects on rewarded task-switching performance, by directly comparing
the group effect in the pre- and post-surgery sessions separately. We anticipated differences
between the sham and lesion group after, but not prior to surgery.