00_MJ_Intro_Budapest16.pptx

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1/03/2016

22

AxeBeam study: biomarkers

Verstraete et al, Br J Cancer. 2015

AXEBeam study

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Translational research

DESTABILIZED VASCULATURE

SUSCEPTIBLE TO BEVACIZUMAB

Inhibit tumor growth

MATURE VASCULATURE

RESISTANT TO BEVACIZUMAB

Support tumor growth

GOOD RESPONDER

BAD RESPONDER