ESTRO
Combined chemo- and radiotherapy treatment:
Cellular / molecular interaction
DNA damage
Chromosome
Cell
Apoptosis
induction repair
aberration
Cycle
5-Fu
MTX
HU
dFdC
F-ara-A
-
?
?
-
-
-/+
?
-/+
-
-
-
?
+
+
+
+
?
+
+
+
?
?
?
-
-?
Antimetabolites