768-769 / 1173
ESTRO
DNA damage
Chromosome Cell
Apoptosis
induction repair
aberration
Cycle
Cis-platinum
BCNU
Cyclophosphamide
+?
?
?
+
+
?
?
-
-
-
?
?
?
?
?
Alkylating agents
Combined chemo- and radiotherapy treatment:
Cellular / molecular interaction