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0%

20%

40%

60%

80%

100%

0

2

4

6

8

10

12

Survival

POG-8631/CCG-923 (

Reduced

Dose

XRT

Alone

, N=46)

CCG-9892

(Reduced Dose

XRT+ Chemo

, N=65)

POG-8631/CCG-923 (

Standard

Dose XRT

Alone

, N=42)

Packer et al. JCO 17: 2127, 1999; Thomas et al. JCO 18: 3004, 2000

Years Post Onstudy

Reduced Dose Radiotherapy Is Feasible in Standard-Risk

Medulloblastomas If Combined with Adjuvant Chemotherapy