81
Biophysical Society 58
th
Annual Meeting, San Francisco, California
M
O
N
D
A
Y
1319-P
os
B
oard
#B49
THERMODYNAMIC CHARACTERIZATION OF PROTEIN
FOLDING USINGMONTE CARLOMETHODS.
Nana M. Heilmann
,
Moritz Wolf, Timo Strunk, Julia Setzler, Martin Brieg, Wolfgang Wenzel
1320-P
os
B
oard
#B50
MECHANISTIC EXPLANATION OF DIFFERENT UNFOLDING
BEHAVIORS OBSERVED FOR TRANSMEMBRANE AND SOLUBLE
β
-BARREL PROTEINS.
Ulf Hensen
, Daniel J. Mueller
1321-P
os
B
oard
#B51
DECIPHERING FOLDING PATHWAYS OF PHAGE T4 LYSOZYME:
INFLUENCE OF MULTIPLE CONFORMATIONS.
Katherina Hemmen
,
Dmitro Rodnin, Daniel Rohrbeck, Soheila Rezaei Adariani,
Hugo Sanabria, Claus A. M. Seidel
1322-P
os
B
oard
#B52
KINETIC OF LOOP FORMATION IN POLYPEPTIDES AND
FREE ENERGY LANDSCAPES.
Emanuele Paci
, James Gowdy
1323-P
os
B
oard
#B53
VOLUME AND ENTHALPY PROFILE OF SURFACTANT-INDUCED
PROTEIN FOLDING IN FERROUS CYTOCHROME-C, USING CO
PHOTO-DISSOCIATIONMETHODS.
Tarah A. Word
, Randy W. Larsen
1324-P
os
B
oard
#B54
COMBINE HIGH-RESOLUTION OPTICAL TWEEZER DATA
WITH PROTEIN CRYSTAL STRUCTURE TO DERIVE ENERGY,
KINETICS, AND STRUCTURE OF CONFORMATIONAL STATES
ALONG PROTEIN FOLDING PATHWAY.
Aleksander Rebane
,
Yongli Zhang
1325-P
os
B
oard
#B55
education
travel
awardee
SUPPRESSION OF PICOSECOND DYNAMICS IN
β
-CASEIN
UPON CALCIUM BINDING.
Stefania Perticaroli,
Jonathan D. Nickels,
Georg Ehlers, Eugene Mamontov, Alexei P. Sokolov
1326-P
os
B
oard
#B56
PARTIAL FOLDING AND UNIQUE ATP FUNCTION IN PROTEIN
PHOSPHATASE 2A LATENCY AND ACTIVATION.
Yongna Xing
Enzyme Inhibition (Boards #B57–#B70)
1327-P
os
B
oard
#B57
MOLECULAR DYNAMICS OF THE DENGUE VIRUS NS3/NS2B
PROTEASE IN PRESENCE OF INHIBITOR OR SUBSTRATE.
Maria Carolina P. Lima
, Gustavo de Miranda Seabra
1328-P
os
B
oard
#B58
DYNAMICAL NETWORK IN HIV-1 PROTEASE AND ITS
MUTANTS: IMPLICATIONS ON DRUG RESISTANCE.
Rajeswari Appathurai
, Sanjib Senapati
1329-P
os
B
oard
#B59
minority affairs travel awardee
UNDERSTANDING THE MOLECULAR MECHANISM OF
SYNERGISTIC INHIBITION IN THE HEPATITIS C VIRUS (HCV)
POLYMERASE USING MOLECULAR DYNAMICS SIMULATIONS
AND FREE ENERGY CALCULATIONS.
Jodian A. Brown
, Ian F. Thorpe
1330-P
os
B
oard
#B60
REGULATORY ELEMENTS OF HCV NS5B POLYMERASE -
β
-LOOP AND C-TERMINAL TAIL - ARE REQUIRED FOR
ACTIVITY OF ALLOSTERIC THUMB SITE II INHIBITORS.
Anita Niedziela-Majka
, Sarah E. Boyce, Neeraj Tirunagari, Jason Perry,
Melanie Wong, Elaine Kan, Leanna Lagpacan, Ona Barauskas,
Magdeleine Magdeleine Hung, Martijn Fenaux, Todd Appleby,
William J. Watkins, Uli Schmitz, Roman Sakowicz
1331-P
os
B
oard
#B61
COMPUTATIONAL THROMBIN INHIBITOR OPTIMIZATION.
Vytautas Gapsys
, Bert de Groot
1332-P
os
B
oard
#B62
PROBING THE LIGAND BINDING MECHANISM OF MNK
INHIBITORS BY DOCKING AND MOLECULAR DYNAMICS
SIMULATIONS.
Srinivasaraghavan Kannan
, Anders Poulsen,
Haiyan Yang, Melvyn Ho, May Ann, Lohitha Rao Chennamaneni,
Jeffrey Hill, Chandra S. Verma, Kassoum Nacro
1333-P
os
B
oard
#B63
DEVELOPMENT OF NOVEL XANTHINE OXIDASE INHIBITORS
WITH RADICAL SCAVENGING PROPERTIES FOR THE
PREVENTION OF REPERFUSION INJURIES.
Stefan Paula
,
Taylor Kidd, Emily Hofmann, Rebekka Meeks, Reid Kline, Thuy Do,
Timothy Dunn, Lili Ma
1334-P
os
B
oard
#B64
DATA MINING THE PDB: PHOSPHORYLATION CAN DIRECTLY
INTERFERE WITH DRUG BINDING.
Kyle P. Smith
,
Kathleen M. Gifford, Julian L. Klosowiak, Sarah E. Rice
1335-P
os
B
oard
#B65
EFFECT OF NATURAL PRODUCT EXTRACTS ON
LIPOXYGENASE, CYCLOOXYGENASE, AND PROTEIN
TYROSINE PHOSPHATASE 1B.
Magdalena M. Siodlak
,
Sharada T. Buddha
1336-P
os
B
oard
#B66
STRUCTURE-THERMODYNAMICS CORRELATIONS OF
FLUORINATED BENZENSULFONAMIDES AS INHIBITORS
OF HUMAN CARBONIC ANHYDRASES.
Daumantas Matulis
,
Joana Gylytė, Asta Zubrienė, Virginija Dudutienė, Alexey Smirnov,
Lena Manakova, Saulius Gražulis
1337-P
os
B
oard
#B67
AN ASYMMETRIC PATTERN IN BINDING OF
PROSTAGLANDIN ENDOPEROXIDE H SYNTHASES TO
THEIR INHIBITORS AND ITS IMPLICATIONS FOR
ENZYME CATALYSIS AND ALLOSTERIC REGULATION.
Inseok Song
1338-P
os
B
oard
#B68
A NOVEL AROMATIC CARBOXYLIC ACID INHIBITS
LUCIFERASE ENZYMATIC ACTIVITY IN
MAMMALIAN CELLS BY ACYLATION OF AN ACTIVE
REGULATORY LYSINE RESIDUE.
Madoka Nakagomi
, Koichi Shudo,
Satoshi Sakamoto, Hiroshi Handa, Takeo Iwamoto, Tomokazu Matsuura
1339-P
os
B
oard
#B69
STRUCTURE ANALYSIS OF HISTIDINE DECARBOXYLASE IN
COMPLEX WITH INHIBITORS.
Hirofumi Komori
, Yoko Nitta,
Hiroshi Ueno, Yoshiki Higuchi
1340-P
os
B
oard
#B70
COVALENT DOCKING OF LARGE LIBRARIES FOR THE DIS-
COVERY OF CHEMICAL PROBES.
Nir London
, Rand M. Miller,
John J. Irwin, Oliv Eidam, Lucie Gibold, Richard Bonnet, Brian K.
Shoichet, Jack Taunton
Membrane Structure, Folding,
and Design (Boards #B71–#B87)
1341-P
os
B
oard
#B71
THERMODYNAMIC AND FUNCTIONAL ANALYSIS
OF CLC DIMERIZATION.
Nicholas B. Last
, Christopher Miller
