76
Biophysical Society 58
th
Annual Meeting, San Francisco, California
1250-P
lat
5:00
pm
ATP ACTS AS SWITCH FOR TOGGLING CALRETICULIN
BETWEEN ITS LECTIN AND CHAPERONE FUNCTION.
Karunesh Arora
, Charles L. Brooks III
1251-P
lat
5:15
pm
ALLOSTERIC OPENING OF THE POLYPEPTIDE-BINDING SITE
WHEN AN HSP70 BINDS ATP.
Qinglian Liu
, Ruifeng Qi, Evans
Sarbeng, Qun Liu, Katherine Le, Xinping Xu, Hongya Xu, Jiao Yang,
Jennifer Wong, Christina Vorvis, Wayne Hendrickson, Lei Zhou
1252-P
lat
5:30
pm
STABILITY AND DYNAMICS OF ALPHA CRYSTALLIN OLIGOMERS
PROBED BY FRET AND FCS REVEAL PERSISTENT
OLIGOMERIZATION UNDER DILUTE CONDITIONS.
Alexander H. Pearlman, Satyajeet Salvi, Patricia B. O’Hara,
James A. Hebda
1253-P
lat
5:45
pm
ENHANCED CHAPERONE CLUSTERING FACILITATES PROTEIN
FOLDING IN THE ENDOPLASMIC RETICULUM OF YEAST.
Marc Griesemer
, Carissa Young, Anne S. Robinson, Linda Petzold
4:00
pm
–6:00
pm
, R
oom
305
Platform
Protein-Lipid Interactions II
Co-Chairs
Jefferson Knight, University of Colorado, Denver
Shelli Frey, Gettysburg College
1254-P
lat
4:00
pm
MOLECULAR MECHANISMS OF HIGH-AFFINITY PHOS-
PHOINOSITIDE BINDING BY THE TANDEM C2 DOMAINS OF
GRANUPHILIN/SLP-4. Tatyana A. Lyakhova,
Jefferson Knight
1255-P
lat
4:15
pm
NMR OF CONDITIONAL PERIPHERAL MEMBRANE PROTEINS.
Krystal A. Morales, Mikaela D. Stewart,
Tatyana I. Igumenova
1256-P
lat
4:30
pm
THE ROLE OF PROTEIN AND MEMBRANE CONTEXT IN THE
INTERACTION OF POLYGLUTAMINE PEPTIDES WITH LIPID
MEMBRANES. Warren A. Campbell,
David Van Doren
,
Kathleen A. Burke, Justin Legleiter, Shelli L. Frey
1257-P
lat
4:45
pm
ASSOCIATION OF
α
-SYNUCLEIN WITH LIPID VESICLES.
STOPPED-FLOW KINETICS OF CONCERTED BINDING AND
CONFORMATIONAL CHANGE.
Thomas M. Jovin
,
Volodymyr V. Shvadchak, Remco Siero, Lisandro J. Falomir-Lockhart,
Vinod Subramaniam
1258-P
lat
5:00
pm
FLUORINATED AROMATIC AMINO ACIDS DISTINGUISH
CATION-π INTERACTIONS FROM MEMBRANE INSERTION.
Tao He
, Anne Gershenson, Jianmin Gao, Mary F. Roberts
1259-P
lat
5:15
pm
INVITRO RECONSTITUTIONOFTRANSCELLULARTUNNELS
CLOSURE.
Coline Prévost
, John Manzi, Hongxia Zhao, Pekka Lappalainen,
Emmanuel Lemichez, Andrew Callan-Jones, Patricia Bassereau
1260-P
lat
5:30
pm
THE ASSEMBLY, STRUCTURE AND ACTIVATION OF
INFLUENZA A M2 TRANSMEMBRANE DOMAIN DEPENDS
ON LIPID MEMBRANE THICKNESS AND COMPOSITION.
Elka R. Georgieva
, Haley D. Norman, Peter P. Borbat, Jack H. Freed
1261-P
lat
5:45
pm
HSP70 ASSOCIATES WITH PHOSPHATIDYLSERINE MEMBRANES
VIA THE PEPTIDE BINDING DOMAIN.
Antonio De Maio
,
Gabrielle Armijo, Victor Lopez, Derek Gonzales, Jonathan Okerblom,
Nelson Arispe, David M. Cauvi
4:00
pm
–6:00
pm
, R
oom
306
Platform
Computational Methods
Co-Chairs
David Mobley, University of California, Irvine
Peter Mulligan, Stanford University
1262-P
lat
4:00
pm
BAYESIAN STRUCTURE DETERMINATION FROM SPARSE
SINGLE MOLECULE X-RAY DIFFRACTION IMAGES.
Michal Walczak
, Helmut Grubmueller
1263-P
lat
4:15
pm
XMDFF: MOLECULAR DYNAMICS FLEXIBLE FITTING OF
LOW-RESOLUTION X-RAY STRUCTURES.
Abhishek Singharoy
,
Ryan McGreevy, Qufei Li, Jingfen Zhang, Eduardo Perozo, Klaus Schulten
1264-P
lat
4:30
pm
I-ATTRACT: A NEW FLEXIBLE DOCKING APPROACH FOR
INVESTIGATING PROTEIN PROTEIN INTERACTIONS.
Christina Schindler
, Martin Zacharias
1265-P
lat
4:45
pm
PREDICTING CHARGED-LIGAND BINDING FROMMOLECULAR
SIMULATIONS.
David L. Mobley
, Gabriel J. Rocklin
1266-P
lat
5:00
pm
RIBOSOMAL KINETICS AND CONCERTED MOTIONS FROM
NANOSECONDS TO SECONDS.
Christian Blau
, Lars V. Bock,
Gunnar F. Schröder, Iakov Davydov, Niels Fischer, Holger Stark,
Marina V. Rodnina, Andrea C. Vaiana, Helmut Grubmuller
1267-P
lat
5:15
pm
ACCELERATE SAMPLING IN ATOMISTIC ENERGY LANDSCAPES
USING TOPOLOGY-BASED COARSE-GRAINED MODELS.
Weihng Zhang
, Jianhan Chen
1268-P
lat
5:30
pm
ANALYSIS OF SIZE AND COMPOSITIONAL DISTRIBUTIONS OF
PLEOMORPHIC ENSEMBLES ARISING FROM CLUSTERING OF
MULTIVALENT BIOLOGICAL MOLECULES.
Cibele V. Falkenberg
,
Michael L. Blinov, Leslie M. Loew
1269-P
lat
5:45
pm
DYNAMIC RE-DISCRETIZATION ALLOWS SIMULATION OF
BIOPOLYMERS ACROSS LENGTH-SCALES.
Peter Mulligan
,
Elena F. Koslover, Andrew J. Spakowitz
5:00
pm
–6:30
pm
, R
oom
123
Exhibitor Presentation
HEKA Elektronik
HEKA Electrophysiology Update
For over 40 years, HEKA Elektronik has provided innovative products,
expert tech support and unmatched service to their customers. HEKA’s
commitment to technological innovation is reflected by consistent updating
of both hardware and software. While yesterday’s gold standards try to keep
pace with the latest research techniques, HEKA takes the lead.
By popular demand, HEKA is hosting a series of user meetings with tutorial
presentations. On one hand, some of the new products will be showcased
