83
Biophysical Society 58
th
Annual Meeting, San Francisco, California
M
O
N
D
A
Y
1367-P
os
B
oard
#B97
LONG-RANGE DISTANCE CONSTRAINTS FOR THE FIBRIL
FOLD OF PARKINSON’S PROTEIN ALPHA-SYNUCLEIN.
Maryam Hashemi Shabestari, Pravin Kumar, Ine M.J. Segers-Nolten,
Mireille M.A.E. Claessens, Bart D. van Rooijen, Vinod Subramaniam,
Martina Huber
1368-P
os
B
oard
#B98
STRUCTURE OF THE TRANSIENT, MEMBRANE-ACTIVE
AMYLOID BETA OLIGOMERS IN PHYSIOLOGICAL SOLUTIONS
PROBED BY A COMBINATION OF FLUORESCENCE AND
SOLID STATE NMR.
Bappaditya Chandra
, Bidyut Sarkar,
Venus Singh, Arghya Mandal, Muralidharan Chandrakesan,
Perunthiruthy K. Madhu, Sudipta Maiti
1369-P
os
B
oard
#B99
SYSTEMATIC CHARACTERIZATION OF WILD TYPE AND
FAMILIAL ALZHEIMER’S DISEASE MUTANT A
β
MONOMERS
THROUGH THE CONVERGENCE OF ENSEMBLES SIMULATED
WITH DIFFERENT FORCE FIELDS.
David J. Rosenman
,
Nicolina Clemente, Chunyu Wang, Angel E. García
1370-P
os
B
oard
#B100
STRUCTURAL AND MECHANISTIC ANALYSES OF THE
EFFECTS OF SMALL COMPOUNDS ON AMYLOID BETA
SELF-ASSEMBLY.
Johnny Habchi
, Priyanka Joshi, Alessandro Spilotros,
Dmitri Svergun, Michele Vendruscolo
1371-P
os
B
oard
#B101
international
travel
awardee
DECOUPLING CONFORMATION, AGGREGATION AND
FUNCTION OF AMYLOID-
β
MONOMERS AND OLIGOMERS:
AN FCS, SERS AND AFM STUDY.
Debanjan Bhowmik
,
Christina MacLaughlin, Gilbert C. Walker, Sudipta Maiti
1372-P
os
B
oard
#B102
TRANSTHYRETIN INTERACTS WITH AMYLOID-
Β
ETA
OLIGOMERS TO DELAY AMYLOID AGGREGATION.
Kanchan Garai
, Xinyi Li, Evan M. Powers, Joel Buxbaum, Rohit Pappu
1373-P
os
B
oard
#B103
AMYLIN INTERACTS WITH A
β
AND MAY ACCELERATE THE
DEVELOPMENT OF DEMENTIA. Kaleena Jackson, Simon Xie,
Florin Despa
1374-P
os
B
oard
#B104
MAPPING THE STRUCTURE OF TAU USING SINGLE
MOLECULE FRET.
Xiaohan Li
, Elizabeth Rhoades
1375-P
os
B
oard
#B105
EXPLORING A TWO-STEP ADSORPTION OF AN INTRINSICALLY
DISORDERED PEPTIDE AT MODEL TEMPLATES.
Prajnaparamita Dhar
, Jordan Hildenbrand
1376-P
os
B
oard
#B106
INCREASED AFFINITY FOR TUBULIN IMPAIRS TAU
FUNCTION.
Elizabeth Rhoades
, Shana Elbaum-Garfinkle,
Garrett Cobb, Jocelyn T. Compton, Xiaohan Li
1377-P
os
B
oard
#B107
education
travel
awardee
STATHMIN EXISTS AS AN OLIGOMER IN SOLUTION, AS
EVIDENCED BY STATIC LIGHT-SCATTERING, NATIVE GEL
ELECTROPHORESIS, AND EPR SPECTROSCOPY.
Ashley J. Chui
,
Katherina C. Chua, Michael D. Bridges
1378-P
os
B
oard
#B108
GLI3/SPOP MULTIVALENT INTERACTIONS ARE
CONCENTRATION-DEPENDENT.
Melissa R. Marzahn
,
Tanja Mittag
1379-P
os
B
oard
#B109
SOLVENT EFFECTS ON THE STRUCTURE AND INTERNAL
DYNAMICS OF CALCITONIN GENE-RELATED PEPTIDE.
Sara M. Sizemore
, Stephanie M. Cope, Anindya Roy,
Giovanna Ghirlanda, Sara M. Vaiana
1380-P
os
B
oard
#B110
MOLECULAR CROWDING STABILIZES BOTH THE
INTRINSICALLY DISORDERED CALCIUM-FREE STATE AND
THE FOLDED CALCIUM-BOUND STATE OF AN RTX PROTEIN:
IMPLICATION FOR TOXIN SECRETION.
Ana Cristina Sotomayor Pérez, Orso Subrini, Audrey Hessel,
Daniel Ladant,
Alexandre Chenal
1381-P
os
B
oard
#B111
STRUCTURAL ENSEMBLES OF INTRINSICALLY DISORDERED
PROTEINS DEPEND STRONGLY ON FORCE FIELD.
Sarah Rauscher
, Vytautas Gapsys, Andreas Volkhardt, Christian Blau,
Bert L. de Groot, Helmut Grubmüller
DNA Replication and Dynamics
(Boards #B112–#B127)
1382-P
os
B
oard
#B112
REPLICATIVE HELICASE ASSISTS DNA POLYMERASE IN
BYPASSING A LESION.
Bo Sun
, James T. Inman, Benjamin Y. Smith,
Yi Yang, Smita S. Patel, Michelle D. Wang
1383-P
os
B
oard
#B113
DNA UNWINDING BY PCRA HELICASE AND REPD USING TIRF
AND MAGNETIC TWEEZERS. Algirdas Toleikis, Simone Kunzelmann,
Gregory I. Mashanov, Martin R. Webb,
Justin E. Molloy
1384-P
os
B
oard
#B114
SINGLE MOLECULE STUDY OF HIV-1 REVERSE
TRANSCRIPTASE POLYMERIZATION ACTIVITY IN THE
PRESENCE OF NC.
Kiran Pant
, Robert J. Gorelick, Ioulia Rouzina,
Mark C. Williams
1385-P
os
B
oard
#B115
A NOVEL FUNCTION OF THE BACTERIAL REPLICATION
INITIATOR PROTEIN DNAA.
Paola E. Mera
, Virginia Kalogeraki,
Lucy Shapiro
1386-P
os
B
oard
#B116
DYNAMICS OF DSDNA BREAK, ORGANIZATION OF THE
NUCLEUS BASED ON POLYMER DYNAMICS.
David Holcman
,
Assaf Amitai
1387-P
os
B
oard
#B117
DNA SECONDARY STRUCTURE FORMATION IN BACTERIAL
GENE CAPTURE SYSTEMS AT SINGLE-MOLECULE
RESOLUTION. Marko Swoboda, Maj Svea Grieb, Varsha Natarajan,
Aleksandra Nivina, Didier Mazel,
Michael Schlierf
1388-P
os
B
oard
#B118
INVESTIGATING THE DYNAMICS OF THE
β
2
SLIDING CLAMP
IN ESCHERICHIA COLI AT THE SINGLE-CELL LEVEL UTILIZ-
ING SINGLE-MOLECULE FLUORESCENCE MICROSCOPY.
SriramTiruvadi Krishnan
, Martin Charl Moolman, JacobW.J. Kerssemakers,
Theo van Laar, Pawel Tulinski, Rodrigo Reyes-Lamothe, David J. Sherratt,
Nynke H. Dekker
1389-P
os
B
oard
#B119
SV40 HELICASE UNWINDS DNA AGAINST FORCE.
Mariana Koeber
, Zhongbo Yu, Kollol Aguan, Bojk Berghuis,
David Dulin, Nynke H. Dekker
