74
Biophysical Society 58
th
Annual Meeting, San Francisco, California
fluid under physiological conditions. In this tutorial, Bruker will present
theories behind AFM, bio-applications in high-speed AFM, and practical
guides to quantitative mechanical measurements and analysis of biologi-
cal samples ranging from a single membrane protein to a single cell.
While the key experiments presented will encompass research in micro-
biology/pain mediation/cancer, the methodology has also been employed
in other disciplines including pathogenesis/stem cell differentiation/cell
signaling and more.
Presenter:
Senli Guo, Application Scientist, Bruker Nano Surfaces
4:00
pm
–5:00
pm
, R
oom
122
Membership Committee Meeting
4:00
pm
–5:00
pm
, R
oom
300
Career Center Workshop
Ten Tough Industrial Interview Questions
(and Ten Pretty Good Responses)
You’ve been invited to interview with that drug development company
that you’ve always wanted to work for. You’ve soaked up the details of the
position description. You are confident in your ability to do the job, as
well as answer any/all technical questions during the interview process.
The day is yours…until…that first question catches you by surprise and
your confidence begins to wilt. Be prepared for those non-technical ques-
tions that you will almost certainly hear at some point, know why they
are asked, and learn what a good (if not great) response to each question
might be by attending this workshop.
4:00
pm
–6:00
pm
, R
oom
134
Symposium
Future of Biophysics Burroughs Wellcome
Fund Symposium
Chair
Robert Nakamoto, University of Virginia Health Science Center
N
o
A
bstract
4:00
pm
“OFF-LABEL” USES OF SEQUENCING TECHNOLOGY TO
EXPLORE THE PHYSICAL GENOME.
William J. Greenleaf
N
o
A
bstract
4:30
pm
SPHINGOLIPID AND CHOLESTEROL DISTRIBUTION IN THE
PLASMA MEMBRANE BY HIGH-RESOLUTION SIMS.
Mary L. Kraft
N
o
A
bstract
5:00
pm
THE INFLUENCE OF EXTRINSIC FLUCTUATIONS ON THE
DECISION OF CELLS.
Elijah Roberts
N
o
A
bstract
5:30
pm
HOW CAN LABILE BONDS LEAD TO TOUGHER NETWORKS?
THE UNEXPECTED ROLE OF CROSSLINKER KINETICS IN
DETERMINING CYTOSKELETAL MECHANICS.
Megan T. Valentine
4:00
pm
–6:00
pm
, R
oom
135
Symposium
Molecular Basis of Voltage Dependence
Co-Chairs
Sudha Chakrapani, Case Western Reserve University
Eduardo Perozo, University of Chicago
1218-S
ymp
4:00
pm
THERMODYNAMIC ANALYSIS OF VOLTAGE-SENSING
MECHANISMS.
Baron Chanda
1219-S
ymp
4:30
pm
STRUCTURAL INVESTIGATION OF A BACTERIAL VOLTAGE-
GATED SODIUM CHANNEL NA
V
RH.
Nieng Yan
, Xu Zhang
1220-S
ymp
5:00
pm
VOLTAGE-SENSOR DOMAIN PROTEINS: PHOSPHOINOSITIDE
SIGNAL, PROTON PERMEATION AND MOLECULAR TOOLS.
Yasushi Okamura
1221-S
ymp
5:30
pm
STRUCTURAL BASIS OF VOLTAGE-DEPENDENT GATING
IN CI-VSP.
Eduardo Perozo
, Qufei Li, Sherry Wanderlin
4:00
pm
–6:00
pm
, R
oom
130/131
Platform
Calcium Signaling
Co-Chairs
Martin Falcke, Max Delbrück Center, Germany
Israel Sekler, Ben Gurion University, Israel
1222-P
lat
4:00
pm
RELIABLE ENCODING OF STIMULUS INTENSITIES BY
RANDOM SEQUENCES OF CA
2+
SPIKES.
Martin Falcke
1223-P
lat
4:15
pm
COUPLING OF CHEMICAL AND MECHANICAL SENSING IN
FIBROBLAST CELLS.
Josephine Lembong
, Bo Sun, Matthew Rogers,
Howard A. Stone
1224-P
lat
4:30
pm
NA
+
CHANNELS CONTROL METABOLISM AND
GLOBAL CA
2+
SIGNALING BY INDUCING NA
+
AND
CA
2+
RESPONSES THAT ARE PROPAGATING INTO
THE MITOCHONDRIA OF BETA CELLS.
Israel Sekler
1225-P
lat
4:45
pm
THE POTENTIAL FOR ANOTHER CALCIUM UPTAKE
MODE IN CARDIAC MITOCHONDRIA.
Christoph A. Blomeyer
, Jason N. Bazil, David F. Stowe, Ranjan K. Dash,
Amadou K. Camara
1226-P
lat
5:00
pm
ULTRAFAST GENETICALLY ENCODED CALCIUM
INDICATORS FOR VISUALIZING CALCIUM FLUX AND
ACTION POTENTIALS.
Nordine Helassa
, Elric Esposito, Tom Carter,
Jonathan Bradley, David Ogden, Katalin Török
1227-P
lat
5:15
pm
A NEW CA
2+
PROBE, CALSTABI-CAM, TARGETED TO
RYANODINE RECEPTORS OF CARDIOMYOCYTES.
Sara Pahlavan
, Yuming Yang, Caitlin Robertson, Naohiro Yamaguchi,
Lars Cleemann, Martin Morad
1228-P
lat
5:30
pm
CAMKII-MEDIATED AMPLIFICATION IS ESSENTIAL TO
NAADP SIGNALLING IN CARDIAC MYOCYTES.
Rebecca A. Bayliss
,
Wee Lin, Emma Bolton, Duncan Bloor-Young, Grant C. Churchill,
Antony Galione, Derek A. Terrar
1229-P
lat
5:45
pm
CALCIUM SIGNALING INSIDE CILIA UPON MECHANICAL
BENDING. Steven Su, Siew Cheng Phua, Robert DeRose,
Takanari Inoue
