70
Biophysical Society 58
th
Annual Meeting, San Francisco, California
1168-S
ymp
11:15
am
TARGETING INFLUX TRANSPORTERS IN THE HUMAN
BLOOD BRAIN BARRIER.
Kathleen Giacomini
1169-S
ymp
11:45
am
NONINVASIVE PERSONALIZED GENOMICS.
Charles Cantor
1170-S
ymp
12:15
pm
TRANSLATING A TRILLION POINTS OF DATA INTO
THERAPIES, DIAGNOSTICS, AND NEW INSIGHTS INTO
DISEASE.
Atul J. Butte
10:45
am
–12:45
pm
, R
oom
135
Symposium
Stochasticity in Cellular Processes
Co-Chairs
Rachel Kuske, University of British Columbia, Canada
Nathalie Questembert-Balaban, Hebrew University of Jerusalem, Israel
N
o
A
bstract
10:45
am
ON THE STATISTICAL NATURE OF BEHAVIORAL DIVERSITY.
Stanislas Leibler
1171-S
ymp
11:15
am
STOCHASTIC BISTABILITY AND SWITCHING IN VIRUS/
IMMUNE CELL NETWORKS.
Elizabeth Read
1172-S
ymp
11:45
am
RELIABILITY OF NOISE-INDUCED SPIKES FOR TWO TYPES
OF THRESHOLD DYNAMICS.
Rachel Kuske
, Na Yu, Yue Xian Li
1173-S
ymp
12:15
pm
DETERMINISTIC VERSUS STOCHASTIC VARIABILITY
IN THE MAMMALIAN CELL CYCLE. Sivan Pearl, Oded Sandler,
Oded Agam, Itamar Simon,
Nathalie Q. Balaban
10:45
am
–12:45
pm
, R
oom
130/131
Symposium
Regulation of Cytoskeletal Motors
Co-Chairs
Marileen Dogterom, AMOLF, The Netherlands
Kazuhiro Oiwa, National Institute of Information and Communications
Technology, Japan
1174-S
ymp
10:45
am
MECHANISTIC INSIGHTS OF DYNEIN MOTOR
ACTION FROM ELECTRON MICROSCOPY STUDIES.
Stanley A. Burgess,
Takahide Kon, Peter J. Knight, Kazuo Sutoh
1175-S
ymp
11:15
am
RECONSTITUTION OF DYNAMIC AXONEMAL COMPLEXITY
WITH USING A BOTTOM UP STRATEGY.
Kazuhiro Oiwa
1176-S
ymp
11:45
am
DYNEIN-MEDIATED POSITIONING OF MICROTUBULE
ASTERS IN 3D CONFINEMENT. Sophie Roth,
Marileen Dogterom
1177-S
ymp
12:15
pm
NEW METHODS FOR MOLECULAR MOTOR AND CELL
MOTILITY RESEARCH. Adam G. Hendricks, John F. Beausang,
John H. Lewis, Lisa Lippert, Deborah Shroder, E. Michael Ostap,
Erika L.F. Holzbaur,
Yale E. Goldman
10:45
am
–12:45
pm
, R
oom
132/133
Platform
Mechanisms of Voltage Sensing and Gating
Co-Chairs
Simon Berneche, University of Basel, Switzerland
Brad Rothberg, Temple University School of Medicine
1178-P
lat
10:45
am
GATING CURRENTS OF MONOMERIC HV CHANNEL REVEALS
A PERMEATION PATHWAY COUPLED TO THE VOLTAGE
ACTIVATION.
David Baez-Nieto
, Ester Otarola, Gustavo Contreras,
Peter Larsson, Ramon Latorre, Carlos Gonzalez
1179-P
lat
11:00
am
THE SPECIALIZED ROLE OF THE S1 TRANSMEMBRANE
SEGMENT IN THE GATING OF THE HV1 PROTON CHANNEL.
Laetitia Mony
, Thomas K. Berger, Ehud Y. Isacoff
1180-P
lat
11:15
am
OPTICALLY MAPPING THE MOVEMENT OF DISCRETE
GATING CHARGES IN SHAKER.
Michael F. Priest
, Francisco Bezanilla
1181-P
lat
11:30
am
MULTI-DIMENSIONAL FREE ENERGY LANDSCAPE OF
VOLTAGE SENSOR DOMAIN ACTIVATION.
Lucie Delemotte
,
Marina Kasimova, Vincenzo Carnevale, Michael L. Klein, Mounir Tarek
1182-P
lat
11:45
am
PROTEIN BACKBONE MUTAGENESIS REVEALS A NOVEL LINK
BETWEEN ION OCCUPANCY AND C-TYPE INACTIVATION IN
K
+
CHANNELS.
Kimberly Matulef
, Alexander G. Komarov,
Francis I. Valiyaveetil
1183-P
lat
12:00
pm
REGULATION OF ION PERMEATION IN THE SELECTIVITY
FILTER OF POTASSIUM CHANNELS.
Simon Berneche
,
Wojciech Wojtas-Niziurski, Florian Heer
1184-P
lat
12:15
pm
INITIAL STEPS OF INACTIVATION AT THE K
+
CHANNEL
SELECTIVITY FILTER. Andrew S. Thomson, Florian T. Heer,
Frank J. Smith, Simon Berneche,
Brad S. Rothberg
1185-P
lat
12:30
pm
MAPPING CONFORMATIONAL STATES IN VDAC1 CHANNEL:
COMPLEXITY OF GATING LANDSCAPE.
Sergei Noskov
,
Oscar Teijido Hermida, Tatiana Rostovtseva, Bezrukov Sergei
10:45
am
–12:45
pm
, R
oom
303
Platform: Member-Organized Session
Mechanics at the Cell Surface
Co-chairs
Jesse Goyette, Oxford University, United Kingdom
Jun Allard, University of California, Irvine
1186-P
lat
10:45
am
ANTIGEN-SPECIFIC TCR-PMHC CATCH TRIGGERS T-CELL
SIGNALING BY RAPIDLY ACCUMULATING SUCCESSIVE BOND
LIFETIMES PROLONGED BY OPTIMAL FORCE. Baoyu Liu,
Wei Chen, Brian D. Evavold,
Cheng Zhu
1187-P
lat
11:00
am
HOW CELLULAR GEOMETRY REGULATES TRACTION STRESSES
IN ADHERENT CELLS.
Patrick W. Oakes
, Shiladitya Banerjee,
M. Cristina Marchetti, Margaret L. Gardel
