92
Biophysical Society 58
th
Annual Meeting, San Francisco, California
1589-P
os
B
oard
#B319
A NOVEL INHIBITORY PATHWAY MODULATES THE
FRACTION OF RELEASE-COMPETENT SYNAPTIC VESICLES.
Victor A. Cazares
, Arasakumar Subramani, Widmann Hoerauf,
Johnny James Saldate, Edward L. Stuenkel
1590-P
os
B
oard
#B320
THE ROLE OF DOC2B IN DEPOLARIZATION-EVOKED AND G
PROTEIN-COUPLED RECEPTOR MODULATED EXOCYTOSIS
IN MOUSE CHROMAFFIN CELLS. Claudia S. Bauer,
Alexander J. Groffen,
Elizabeth P. Seward
Nucleo-Cytoplasm Transport
(Boards #B321–#B326B)
1591-P
os
B
oard
#B321
A RAN-DEPENDENT IMPORTIN-BETA/NUP153 BARRIER IN
THE NUCLEAR PORE COMPLEX.
Jeffrey H. Tang
, Alan R. Lowe,
Jaime Yassif, Michael Graf, William Y. C. Huang, Jay T. Groves,
Karsten Weis, Jan T. Liphardt
1592-P
os
B
oard
#B322
CONFORMATIONAL BEHAVIOR OF THE CONFINED
FG-REPEAT DOMAINS IN THE NUCLEAR PORE.
Ruhollah Moussavi-Baygi,
Mohammad R. Mofrad
1593-P
os
B
oard
#B323
SIMPLE PHYSICAL CONSIDERATIONS EXPLAIN THE
CONFORMATIONAL TRANSITIONS OF THE FG-
NUCLEOPORINS INDUCED BY THE TRANSPORT FACTORS.
Anton Zilman
, Michael Opferman, David Jasnow, Rob Coalson
1594-P
os
B
oard
#B324
CHARACTERIZATION OF THE SELECTIVE BARRIER IN
NUCLEAR PORE COMPLEX.
Jiong Ma
, Alexander Goryaynov,
Weidong Yang
1595-P
os
B
oard
#B325
COMPUTATIONAL STUDY OF BINDING BETWEEN DDX3
AND HIV-1 MRNA NUCLEOCYTOPLASMIC EXPORT
COMPLEX.
S. Hanif Mahboobi
1596.1-P
os
B
oard
#B326A
CELLULAR METABOLISM FLUIDIZES THE GLASSY BACTERIAL
CYTOPLASM.
Bradley Parry
, Ivan Surovtsev, Matthew Cabeen,
Corey O’Hern, Eric Dufresne, Christine Jacobs-Wagner
1596.2-P
os
B
oard
#B326B
cpow
travel
awardee
LAMIN-A IS MECHANOSENSITIVE TO MATRIX STIFFNESS
AND COUPLES TO THE RETINOIC ACID PATHWAY IN
DIFFERENTIATION.
Irena L. Ivanovska,
Joe Swift,
Dennis E. Discher
Calcium Release Activated Calcium
Channels (Boards #B327–#B347)
1597-P
os
B
oard
#B327
STRUCTURAL MODELING OF HEXAMERIC AND
TETRAMERIC ION CONDUCTION PATHWAYS OF ORAI1
CHANNEL.
Alla Fomina
, Vladimir Yarov-Yarovoy
1598-P
os
B
oard
#B328
COMPLEX FUNCTION OF STIM1 IN THE ACTIVATION
OF STORE-INDEPENDENT ORAI CHANNELS.
Xuexin Zhang
,
Wei Zhang, José González-Cobos, Mohamed Trebak
1599-P
os
B
oard
#B329
DISTINCT ORAI-COUPLING DOMAINS IN STIM1 AND STIM2
DEFINE THE ORAI-ACTIVATING SITE.
Xizhuo Wang
, Youjun
Wang, Yandong Zhou, Eunan Hendron, Salvatore Mancarella,
Mark D. Andrake, Brad S. Rothberg, Jonathan Soboloff, Donald L. Gill
1600-P
os
B
oard
#B330
STIM1 CYTOSOLIC COILED-COIL INTERACTIONS IN THE
RESTING AND ACTIVATED STATE.
Marc Fahrner
, Martin Muik,
Rainer Schindl, Carmen Hoeglinger, Christoph Romanin
1601-P
os
B
oard
#B331
STIM1 BINDS TO PAIRS OF ORAI1 SUBUNITS TO OPEN THE
CRAC CHANNEL.
Michelle Yen
, Ludmila A. Lokteva, Richard S. Lewis
1602-P
os
B
oard
#B332
MECHANISM OF ACTIVATION OF CALCIUM CHANNEL
ORAI1 BY ITS REGULATORY PARTNER STIM1.
Aparna Gudlur
,
Ariel Quintana, Yubin Zhou, Anjana Rao, Patrick G. Hogan
1603-P
os
B
oard
#B333
MECHANISM OF ACTIVATION OF STORE-OPERATED
CALCIUM ENTRY BY 2-AMINOETHOXYDIPHENYL BORATE.
Yandong Zhou
, Youjun Wang, Xizhuo Wang, Lucas Occhiena,
Daniel Y. Chung, Aomin Sun, Donald L. Gill
1604-P
os
B
oard
#B334
EXPLORING THE ROLE OF PORE WATERS AND
COUNTERIONS IN THE CALCIUM RELEASE-ACTIVATED
CALCIUM CHANNEL CONDUCTANCE WITH
COMPUTATION.
Hao Dong
, Giacomo Fiorin, Michael L. Klein
1605-P
os
B
oard
#B335
PH DEPENDENCE OF ORAI1 AND ORAI3 STORE-OPERATED
CURRENT.
Andriy V. Yeromin
, Olga Safrina, Michael D. Cahalan
1606-P
os
B
oard
#B336
DISSECTING THE MOLECULAR MECHANISM OF 2-APB-IN-
DUCED INHIBITION OF STIM1-ORAI1 COUPLING.
Youjun Wang
, Xizhuo Wang, Yandong Zhou, Eunan Hendron,
Lucas Occhiena, Ming Wei, Donald L. Gill
1607-P
os
B
oard
#B337
ORAI3 TM3 POINT MUTATION G158C ALTERS KINETICS OF
2-APB-INDUCED GATING BY DISULFIDE BRIDGE FORMATION
WITH TM2 C101.
Anna Amcheslavsky
1608-P
os
B
oard
#B338
INTERPLAY OF ORAI1-LOOP3 WITH EXTRACELLULAR CA
2+
BINDING SITES IN LOOP1 CONTROLS CRAC CHANNEL
ACTIVITY.
Irene Frischauf
, Rainer Schindl, Vasilina Zayats,
Michael Deix, Anna Hochreiter, Barbora Svobodova, Rüdiger Ettrich,
Christoph Romanin
1609-P
os
B
oard
#B339
NOVEL TRANS-MEMBRANE MUTATION SWITCHES ORAI1
TO A CONSTITUTIVELY ACTIVE AND CA
2+
SELECTIVE
CHANNEL.
Rainer Schindl
, Irene Frischauf, Vasilina Zayats,
Barbora Svobodova, Michael Deix, Martin Muik, Anna Hochreiter,
Rüdiger Ettrich, Christoph Romanin
1610-P
os
B
oard
#B340
ATOMISTIC MOLECULAR DYNAMICS SIMULATIONS OF
DROSOPHILA ORAI IN A HYDRATED LIPID BILAYER.
Mona L. Wood
, Anna Amcheslavsky, Eric Wong, J. Alfredo Freites,
Michael D. Cahalan, Douglas J. Tobias
