97
Biophysical Society 58
th
Annual Meeting, San Francisco, California
M
O
N
D
A
Y
1707-P
os
B
oard
#B437
ACTIVATION AND SENSITIZATION OF THE CAPSAICIN
RECEPTOR TRPV1 BY ALLYL ISOTHIOCYANATE.
Yeranddy A. Alpizar, Maarten Gees, Brett Boonen, Alicia Sanchez,
Bernd Nilius, Thomas Voets,
Karel Talavera
1708-P
os
B
oard
#B438
MOLECULAR ADAPTATIONS TO EXTREME THERMOGENESIS
IN MAMMALIAN HIBERNATORS.
Willem J. Laursen
, Owen Funk,
Jena Goodman, Dana K. Merriman, Nicholas T. Ingolia,
Sviatoslav N. Bagriantsev, Elena O. Gracheva
Ligand-gated Channels II
(Boards #B439-#B466)
1709-P
os
B
oard
#B439
TRANSPORT OF ANTIBIOTICS THROUGH THE SUBSTRATE
SPECIFIC OPRD CHANNEL OF PSEUDOMONAS AERUGINOSA.
Susruta Samanta
, Matteo Ceccarelli
1710-P
os
B
oard
#B440
EXPRESSION, PURIFICATION AND STABILIZATION OF THE
MOUSE 5HT3 RECEPTOR. Gherici Hassaine, Cedric Deluz,
Alexandra Graff, Christophe Moreau, Romain Wyss, Luigino Grasso,
Aline Desmyter, Takashi Tomizaki, Xiao-Dan Li, Henning Stahlberg,
Horst Vogel,
Hugues Nury
1711-P
os
B
oard
#B441
SUBUNIT-DEPENDENT INHIBITION OF NEURONAL NICOTINIC
ACETYLCHOLINE RECEPTORS BY PHILANTHOTOXINS.
Hamid S. Kachel
, Henrik Franzyk, Kristian Strømgaard,
Denis B. Tikhonov, Ian R. Mellor
1712-P
os
B
oard
#B442
STUDIES ON FAST NACH RECEPTOR KINETICS UTILIZING A
NEW APPROACHTO ULTRA-FAST COMPOUND APPLICATIONS
IN AUTOMATED PATCH CLAMP.
Timm Danker
, Elke Guenther
1713-P
os
B
oard
#B443
ASYMMETRIC AGONIST SELECTIVITY OF AGONIST SITES IN
(
α
4
β
2)2
α
4 NICOTINIC ACETYLCHOLINE RECEPTORS: A KEY
DETERMINANT OF AGONIST EFFICACY.
Simone Mazzaferro,
Federica Gasparri, Karina New, Constanza Alcaino, Isabel Bermudez
1714-P
os
B
oard
#B444
LINEAR FREE ENERGY RELATIONSHIPS FOR
NEUROTRANSMITTER BINDINGTO A NICOTINIC
ACETYLCHOLINE RECEPTOR.
Prasad Purohit
, Shaweta Gupta,
Iva Bruhova, Anthony Auerbach
1715-P
os
B
oard
#B445
ENERGY MAPS OF ACETYLCHOLINE RECEPTOR GAT-
ING. Prasad Purohit, Shaweta Gupta, Snehal Jadey,
Anthony Auerbach
1716-P
os
B
oard
#B446
GATING PHI VALUES IN THE MUSCLE ACETYLCHOLINE
RECEPTOR
α
M2-
α
M3 LINKER WITH VS. WITHOUT
AGONISTS.
Shaweta Gupta
, Anthony Auerbach
1717-P
os
B
oard
#B447
FUNCTIONAL ASYMMETRY OF AGONIST BINDING IN FETAL
AND ADULT MUSCLE ACETYLCHOLINE RECEPTORS.
Tapan K. Nayak
, Shaweta Gupta, Anthony Auerbach
1718-P
os
B
oard
#B448
ACIDIC SIDE-CHAIN ROTAMERS AND THEIR IMPACT ON ION
CONDUCTION THROUGH THE NICOTINIC ACETYLCHOLINE
RECEPTOR.
Tyler J. Harpole
, Claudio Grosman
1719-P
os
B
oard
#B449
education
travel
awardee
NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS:
THE DEVELOPMENT OF METHODS FOR PRODUCING
AFFINITY-PURIFIED AND LIPID-RECONSTITUTED
RECEPTORS THAT RETAIN FUNCTIONALITY.
Akash Pandhare
,
Steven Riela, Michaela Jansen, Michael P. Blanton
1720-P
os
B
oard
#B450
STOICHIOMETRY FOR ACTIVATION OF NEURONAL ALPHA7
NICOTINIC RECEPTORS.
Natalia Andersen
, Jeremias Corradi,
Steven Sine, Cecilia B. Bouzat
1721-P
os
B
oard
#B451
PROGRESIVE ANALYSIS OF NACHR STABILITY IN THE LIPIDIC
CUBIC PHASE: NACHR DETERGENT SOLUBILIZATION
AND FRACTIONAL MOBILITY.
Luis F. Padilla-Morales
,
Joel E. González Nieves, Claudia Lanauze, Carlos A. Báez-Págan,
Orestes Quesada-González, Jose A. Lasalde-Dominicci
1722-P
os
B
oard
#B452
CALCULATION OF CHOLESTEROL BINDING AFFINITY FOR
PENTAMERIC LIGAND-GATED ION CHANNELS.
Reza Salari
,
Jerome Henin, Grace Brannigan
1723-P
os
B
oard
#B453
AGONIST RESPONSE INDUCED BY NICOTINIC ALPHA-7
AGONIST IS INHIBITED BY ANTIPSYCHOTIC DRUGS.
Kristen Frederiksen
, Maja Jessen, Jonatan Fullerton Støier,
Kim Dekermendjian, John Paul Redrobe, Christoffer Bundgaard,
Jørgen Calí Eskildsen, Jesper Frank Bastlund
1724-P
os
B
oard
#B454
THE ROLE OF THE FIFTH SUBUNIT ON SENSITIVITY OF
α
4
β
2-
CONTAINING NICOTINIC ACETYLCHOLINE RECEPTORS TO
ALLOSTERIC MODULATORS.
Constanza Alcaino
1725-P
os
B
oard
#B455
AN INTEGRATIVE MODEL OF THE PLEIOTROPIC EFFECTS
OF GENISTEIN AND CYCLOSPORINE A IN FUNCTIONAL
UPREGULATION OF ALPHA 7 NACHRS.
Joseph Farley
,
Mohammad Faridul Islam, Patrick Beard Schwartz, Kristi DeBoeuf,
Jed Rose
1726-P
os
B
oard
#B456
STRUCTURE FUNCTION STUDIES AT TWO DIFFERENT
NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES.
Michael R. Post
, Henry A. Lester, Dennis A. Dougherty
1727-P
os
B
oard
#B457
IDENTIFYINGMOTIFS ESSENTIAL FOR SELECTIVE ACTIVATION
OF NICOTINIC ACETYLCHOLINE RECEPTORS.
Christopher Marotta
, Henry A. Lester, Dennis A. Dougherty
1728-P
os
B
oard
#B458
education
travel
awardee
INSIGHTS INTO THE DISTINCTLY DIFFERENT
SENSITIVITIES OF
α
7 AND
α
7
β
2 NACHRS TO THE
VOLATILE ANESTHETIC ISOFLURANE.
David D. Mowrey
,
QiangLiu, Vasyl Bondarenko, Qiang Chen, Edom Seyoum, Yan Xu,
Jie Wu, Pei Tang
1729-P
os
B
oard
#B459
FUNCTIONAL CHIMERAS OF THE HUMAN
α
7
ACETYLCHOLINE RECEPTOR PROVIDE INSIGHTS
INTO ALLOSTERIC MODULATION.
Edom Seyoum
,
Tommy S. Tillman, Yan Xu, Pei Tang
