94
Biophysical Society 58
th
Annual Meeting, San Francisco, California
1634-P
os
B
oard
#B364
INCREASED SERCA PUMP EXPRESSION IS ASSOCIATED WITH
SLOW TERMINATION OF CALCIUM SPARKS AND DELAYED
LOCAL RECOVERY IN VASCULAR SMOOTH MUSCLE CELLS
OF HYPERTHYROID RATS. Miyamin J. Miranda-Saturnino,
David R. de Alba-Aguayo, Martha Mercado-Morales,
Agustín Guerrero-Hernández,
Angelica Rueda
1635-P
os
B
oard
#B365
ULTRAFAST CALCIUM WAVE IN CULTURED VASCULAR
SMOOTHMUSCLE CELLS.
Jean-Jacques Meister
, Jairo Camilo Quijano
1636-P
os
B
oard
#B366
ALTERED CAMKII AND ROS MICRODOMAINS FAVOR SPARKS
IN ORPHANED RYR AFTER MYOCARDIAL INFARCTION.
Eef Dries
, Ilse Lenaerts, Niall Macquaide, Demetrio Santiago, Piet Claus,
Karin R Sipido
1637-P
os
B
oard
#B367
CAMKII EXACERBATES CALCIUMWAVES DURING REPERFUSION
OF ISCHEMIC HEART. Carlos A. Valverde, Alicia Mattiazzi,
Ariel L. Escobar
1638-P
os
B
oard
#B368
STRETCH-DEPENDENT REGULATION OF CALCIUM
SIGNALING IN HEART - WHO ARE THE KEY PLAYERS?
Benjamin L. Prosser
, Christopher W. Ward, Jaclyn P. Kerr, Guoli Shi,
W. Jonathan Lederer
1639-P
os
B
oard
#B369
THE COUPLED-PACEMAKER CLOCK SYSTEM OF SINOATRIAL
NODAL CELLS REGULATES BOTH THE ACTION POTENTIAL
RATE AND RHYTHM. Yael Yaniv, Alexey E. Lyashkov, Syevda Sirenko,
Yosuke Okamoto, Toni-Rose Guiriba,
Edward G. Lakatta
1640-P
os
B
oard
#B370
INCREASED RISK OF ATRIAL FIBRILLATIONWITH ATTENUATED
ACTIVITY OF P21-ACTIVATED KINASE.
Jaime DeSantiago
, Dan J. Bare,
Yunbo Ke, R. John Solaro, Boaz Avitall, Rishi Arora, Kathrin Banach
1641-P
os
B
oard
#B371
PRO-ARRHYTHMIC CALCIUM WAVES INDUCED BY
PHOSPHODIESTERASE TYPE 4 INHIBITION UPON
BETA-ADRENERGIC STIMULATION INVOLVE BOTH PKA
AND CAMKII.
Pierre Bobin
, Audrey Varin, Rodolphe Fischmeister,
Grégoire Vandecasteele, Jérôme Leroy
1642-P
os
B
oard
#B372
SERCA STIMULATION INCREASES INTRA-SR CA
2+
THRESHOLD
FOR CA
2+
WAVES IN CADIOMYOCYTES.
Miguel Fernandez-Tenorio
,
Ernst Niggli
1643-P
os
B
oard
#B373
CALCIUM HANDLING IS ALTERED IN THE ACTC E99K
TRANSGENIC MOUSE MODEL OF HYPERTROPHIC
CARDIOMYOPATHY.
Christina T. Rowlands
, Steve B. Marston,
Kenneth T. MacLeod
1644-P
os
B
oard
#B374
MULTISPOT MULTIPHOTON CA
2+
IMAGING IN ACUTE
MYOCARDIAL SLICES OF CPVT HEARTS.
Giulia Borile
,
Andrea Urbani, Claudio De Mauro, Domenico Alfieri, Jon W. Lederer,
Francesco Pavone, Marco Mongillo
1645-P
os
B
oard
#B375
EFFECTS OF FLECAINIDE AND RANOLAZINE ON
INTRACELLULAR CALCIUM HANDLING AND SARCOLEMMAL
SODIUM CURRENT.
Anita Alvarez-Laviada
, Markus Sikkel,
Becker Al-khayatt, Ken T. MacLeod
1646-P
os
B
oard
#B376
ATRIAL EXCITATION-CONTRACTION COUPLING AND CA
WAVE PROPAGATION IN NORMAL AND FAILING HEARTS.
Felix Hohendanner
, Lothar A. Blatter
1647-P
os
B
oard
#B377
STRUCTURAL AND FUNCTIONAL ARRANGEMENTS OF
ATRIAL MYOCYTES THAT FACILITATE EXCITATION-
CONTRACTION COUPLING.
Joshua T. Maxwell
,
Felix Hohendanner, Lothar A. Blatter
1648-P
os
B
oard
#B378
IP3 RECEPTOR MEDIATED CA RELEASE IN ATRIAL CELLS
FROM NORMAL AND FAILING HEARTS.
Felix Hohendanner
,
Lothar A. Blatter
Voltage-gated Na Channels II
(Boards #B379–#B397)
1649-P
os
B
oard
#B379
FREQUENCY-DEPENDENT INHIBITION OF SODIUM
CHANNELS BY THE GENERAL ANESTHETIC ISOFLURANE.
Kerry Purtell
, Karl F. Herold, Wei Ouyang, Kevin J. Gingrich,
Hugh C. Hemmings Jr.
1650-P
os
B
oard
#B380
PHARMACOLOGY OF HETEROLOGOUSLY EXPRESSED
HUMAN NA
V
1.9 CHANNELS.
Carlos G. Vanoye
, George R. Ehring,
Alfred L. George
1651-P
os
B
oard
#B381
BLOCK OF NACHBAC BY CADMIUM AND LANTHANUM IONS.
Sun Huang, Kevin Jia,
Robert J. French
1652-P
os
B
oard
#B382
MECHANISM OF SLOW REPRIMING OF NAV CHANNELS BY
LIDOCAINE.
Vaibhavkumar S. Gawali
, Péter Lukács, René Cervenka,
Xaver Koenig, Lena Rubi, Karlheinz Hilber, Eugen Timin, Hannes Todt
1653-P
os
B
oard
#B383
FLUOXETINE BLOCKS NA
V
1.5 CHANNELS VIA A MECHANISM
SIMILAR TO THAT OF CLASS 1 ANTIARRHYTHMICS.
Hugo Poulin, Olivier Theriault, Martin J. Beaulieu,
Mohamed Chahine
1654-P
os
B
oard
#B384
PROTEIN-PROTEIN INTERACTIONS BASED DRUG DISCOVERY
AGAINST THE VOLTAGE-GATED SODIUM CHANNEL.
Syed R. Ali
, Neli Panova, Svetla Stoilova-McPhie, Fernanda Laezza
1655-P
os
B
oard
#B385
SPECIFICITY OF CALMODULIN RECOGNITION OF HUMAN
VOLTAGE-GATED SODIUM CHANNELS.
Dagan C. Marx
,
Mark S. Miller, Liam Hovey, Kristin M. Tefft, Jesse B. Yoder, Elaine Kim,
Sterling C. Martin, Michael D. Feldkamp, Madeline A. Shea
1656-P
os
B
oard
#B386
BLOCK OF NA+ CURRENTS AND SUPPRESSION OF ACTION
POTENTIALS IN CULTURED HIPPOCAMPAL NEURONS BY
GS-458967.
Ryoko Hirakawa
, Luiz Belardinelli, Sridharan Rajamani
1657-P
os
B
oard
#B387
CARDIAC SODIUM CHANNEL DISPLAY COUPLED GATING.
Jerome Clatot
, Haiyan Liu, Eckhard Ficker, Isabelle Deschenes
1658-P
os
B
oard
#B388
THE TRPA1 AGONIST CINNAMALDEHYDE ACTS AS A LOCAL
ANESTHETIC INHIBITINGVOLTAGE-GATED SODIUMCHANNELS
IN SENSORY NEURONS.
Brett Boonen
, Yeranddy A. Alpizar,
Veronick Benoy, Ludo Van Den Bosch, Thomas Voets, Karel Talavera
