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• No data on the overall frequency of re-irradiation in clinical

practice

• However, even in a palliative setting of spinal metastases

Ø

Re-irradiation is practiced in only few patients:

After multiple fraction RT:

8%

After Single fraction RT: SF:

20%

Chow JCO 2007

Most likely explanation:

Ø

Risk / fear of severe normal tissue complication

ESTRO SBRT 2017 - Matthias Guckenberger

11

Frequency of re-RT for vertebral

metastases

07.09.17

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Topics

1.Normal tissue tolerance in re-

irradiation

2.Re-

irradiation of spinal metastases

3.Re-

irradiation of NSCLC

ESTRO SBRT 2017 - Matthias Guckenberger

12

07.09.17