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Radiation induced myelopathy
• Appearance of signs/symptoms of sensory or motor deficits,
loss of function or pain
• Confirmed by magnetic resonance imaging
• Occurs 6 months to 3 years after RT
ESTRO SBRT 2017 - Matthias Guckenberger
17
07.09.17
/
Spinal cord tolerance in primary radiotherapy
50Gy
0.2%
60Gy
6%
Risk of
myelopathy
Conversion of physical doses into 2Gy equivalent doeses:
Ø
LQ model with α/β ~ 2Gy
Kirkpatrick QANTEC IJROBP 2005
ESTRO SBRT 2017 - Matthias Guckenberger
18
07.09.17