1259 / 1578
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Spinal cord tolerance:
re-irradiation with hypofractionation ( SBRT)
Sahgal IJROBP 2010:
Case-control study:
• 5 cases of RM after SBRT
• Thecal sack as OAR
• Maximum dose to thecal sack
• 2Gy equivalent with α/β=2Gy
Clinical Practice:
0% risk of myelopathy if
Ø
Initial course <50Gy (EQD2/2)
Ø
SBRT course <25Gy (EQD2/2)
Ø
Interval >5 months
ESTRO SBRT 2017 - Matthias Guckenberger
21
07.09.17
/
Topics
1.Normal tissue tolerance in re-
irradiation
2.Re-irradiation of spinal metastases
3.Re-irradiation of NSCLC
ESTRO SBRT 2017 - Matthias Guckenberger
22
07.09.17