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INFORMS Philadelphia – 2015

48

SA32

3 - Balanced Tree Partitioning with Compact Mathematical

Programming Formulations

Onur Seref, Virginia Tech, 2060 Pamplin Hall (0235), Blacksburg,

VA, 24061, United States of America,

seref@vt.edu

, J. Paul Brooks

In this paper, we study mathematical programming formulations for the balanced

subtree partitioning problem, some variations of which are known to be NP-

complete. We introduce compact exact mixed integer programming formulations

for different variations of the problem. We explore the effect of different sets of

constraints on our formulations and provide comparative computational results

among our formulations as well as other exact formulations and approximation

algorithms.

SA32

32-Room 409, Marriott

Data Mining in Medical and Brain Informatics

Sponsor: Data Mining

Sponsored Session

Chair: Sina Khanmohammadi, SUNY Binghamton, 4400 Vestal

Parkway East, Binghamton, NY, 13902, United States of America,

skhanmo1@binghamton.edu

Co-Chair: Chou-An Chou, Binghamton University, 4400 Vestal

Parkway, Vestal, NY, United States of America,

cachou@binghamton.edu

1 - Nonlinear Dimensionality Reduction for Analysis of

Electroencephalography Records

Anton Kocheturov, Research Assistant, Department of Industrial

and Systems Engineering, University of Florida, 303 Weil Hall,

Gainesville, FL, 32611-6595, United States of America,

antrubler@gmail.com

We suggest using nonlinear dimensionality reduction technique called the Local

Linear Embedding for analysis of EEG records. This approach enabled us to

distinguish between different states of the brain in a more efficient way

comparing to the existing machine learning techniques since it is faster and

doesn’t require training of the algorithm. We also detected evidence for local

linearity of the brain in the resting state and introduced a new model of the brain

based on it.

2 - The Gap Statistics for Determining the Number of Linear

Autoregressive Modes in a Multimode Model

Vahid Tarokh, Professor, Harvard University, 33 Oxford Street,

MD347, Cambridge, MA, 02138, United States of America,

vahid@seas.harvard.edu

, Jie Ding, Mohammad Noshad

We consider modeling of non-stationary stochastic-processes using a multi-mode

linear autoregressive (AR) model. Each process is modeled as a mixture of

unknown AR components (modes) with an unknown number of modes. We are

interested in online determination of the number of modes, and also in

identification of each mode. A new model selection approach based on GAP

statistics for this purpose is introduced with applications in modeling and

prediction of financial and biological data, etc.

3 - Online Machine Learning Framework for Detecting

EEG Abnormalities

Sina Khanmohammadi, SUNY Binghamton, 4400 Vestal Parkway

East, Binghamton, NY, 13902, United States of America,

skhanmo1@binghamton.edu

, Chou-An Chou

Electroencephalogram (EEG) signals provide insight about human brain function.

EEG signal abnormalities can be a sign of mental disorders such as depression,

epilepsy, etc. Hence, detecting EEG abnormalities can be beneficial for diagnosis,

prognosis, and overall improvement of patient’s quality of life. In this work, we

present a new online classification framework to detect EEG signal abnormalities

in real time. The proposed framework is validated using public EEG datasets.

SA33

33-Room 410, Marriott

Health Policy/ Public Health

Sponsor: Health Applications

Sponsored Session

Chair: Ozge Karanfil, PhD Candidate, MIT Sloan School of

Management, 100 Main Street, E62-379, Cambridge, MA, 02142,

United States of America,

karanfil@mit.edu

1 - Multi-Criteria, Multi-Place, Multi-Time: Evaluating System

Strategies with the Rethink Health Model

Jack Homer, Owner, Homer Consulting, 72 Station Hill Rd.,

Barrytown, NY, 12507, United States of America,

jhomer609@gmail.com,

Gary Hirsch, Bobby Milstein

The ReThink Health Dynamics Model simulates many possible interventions to

improve a local health system by lowering costs and deaths and boosting equity

and productivity through 2040. It has been carefully calibrated to represent

several localities across the U.S. A multi-criteria weighting scheme reflecting local

values helps to select a single “best” intervention strategy. The best strategy may

also depend upon a locality’s room for improvement with regard to health care

and health risks.

2 - Systems Models of Post-traumatic Stress Disorder

Navid Ghaffarzadegan, Professor, Virginia Tech, 231 Durham Hall,

1185 Perry Street, Blacksburg, VA, 24060,

United States of America,

navidg@vt.edu

, Richard Larson

Little agreement exists about effective methods of screening for PTSD, optimal

cutoff values, and even the number of PTSD patients. In a series of modeling

efforts, we uncover five vicious cycles that inhibit PTSD treatment, and

investigate characteristics of an optimal cutoff value for screening. We then show

a population level model of PTSD patients in a military/post-military system. The

models represent different levels of complexities of PTSD at individual and

societal levels.

3 - Patient Flows in Mental Health Clinics

Anne Claire Collin, Graduate Student, MIT, 235 Albany Street,

Ashdown House #5052, Cambridge, MA, 02139,

United States of America,

acollin@mit.edu

There are different factors that can hinder access and quality of care for veterans

in a mental health clinic, many of which are not related to the treatment itself.

The purpose of this research is to analyse the flows of patients in Veterans Affairs’

Mental Health clinics in order to improve access. After a thorough work of

understanding patients’ conditions and paths through the different services,

simulation is used to find a configuration which improves wait times.

4 - Cost Escalation in Health Systems Dominated by

Private Health Insurance

Nisa Onsel, Research Assistant, Bogazici University, Bogazici

University, Industrial Engineering Dept, Bebek, Istanbul, 34342,

Turkey,

nisa.guler@boun.edu.tr

, Yaman Barlas, Günenç Yöcel

Adverse selection and moral hazard are effective in individuals’ health insurance

plan choice and healthcare service utilization. The inefficient behaviors have a

potential impact on increasing insurance premiums. In the existence of increasing

healthcare costs due to advanced health technologies, cost escalation in health

systems is a complex problem. A system dynamics model is constructed and

analyzed for understanding financial sustainability of health systems dominated

by private insurance.

SA34

34-Room 411, Marriott

Health-care Decision Making

Sponsor: Health Applications

Sponsored Session

Chair: Ebru Bish, Associate Professor, Virginia Tech, Dept of Industrial

and Systems Eng, 250 Durham Hall, Blacksburg, VA, 24061-0118,

United States of America,

ebru@vt.edu

1 - The Management of Mass Casualty Incident Response

Behrooz Kamali, PhD Candidate, Virginia Tech, 250 Durham Hall

(MC 0118), Blacksburg, VA, 24061, United States of America,

kamali@vt.edu,

Douglas Bish

In this research we seek to systematically investigate triage and transport of

casualties in the aftermath of a mass-casualty incident. We study the structure of

the optimal policies using novel models that incorporate available resources,

quantity, and mix of casualties. Insights gained allow us to derive special cases

that can be solved to optimality with simple heuristics. We compare results from

our models to that of other models in the literature and the current practices.

2 - A Study on the Spatial Spread and Optimal Control of the 2014-

2015 Ebola Outbreak in West Africa

Esra Buyuktahtakin, Assistant Professor, Wichita State University,

1845 N Fairmount, Wichita, KS, 67260, Wichita, United States of

America,

Esra.Buyuktahtakin@wichita.edu

, Eyyub Kibis,

Emmanuel Des-bordes

We develop an optimization approach to capture the disease dynamics of the

deadly Ebola virus. We illustrate our model on a case study from Guinea, Liberia,

and Sierra Leone. Numerical results demonstrate the accuracy of our predictions

and suggest that the model can be used as a decision-making tool to optimally

allocate resources for epidemic prevention and control.