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S793

ESTRO 36

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Material and Methods

Five preliminary sensitivity test scenarios were created

from a baseline plan modifying each MLC segment by

introducing increasing shifts in leaves positions (0.5 mm -

2 mm). The baseline and test plans were delivered to an

Octavius 1000SRS array (PTW) as well as to EBT3 films. An

average correction was applied to 1000SRS results to

account for the response dependence on source-detector-

distance (SDD) [O. Blanck

et.al

. Phys Med 2016]. The same

five test plans were delivered a second time to the

1000SRS re-orienting all beams perpendicularly to the

array (nominal position) to eliminate SDD and angle

dependence. As a second step 40 clinical MLC plans

optimized for various treatment sites (liver, spine,

prostate) were delivered to the liquid ion chamber array

for patient-specific QA using both the clinical beam

orientations and the beam “nominal position”. For the

latter only a subset of segments(18-21) was selected.

Finally, for 15 out of 40 clinical plans a film-based DQA

was also performed. All results were analyzed using (2%,

2mm),( 3%, 1mm) and (2%, 1mm) gamma index criteria [O.

Blanck

et.al

. Phys Med 2016].

Results

The pass-rate reductions from the baseline,obtained

delivering the five test plans, are shown in fig.1 for (3%,

1mm) gamma criteria. The Octavius 1000SRS showed a

good sensitivity to simulated delivery errors with pass-rate

reductions increasing from 1.7% to a maximum of 43% with

increasing leaves shifts (0.5 mm - 2 mm). Similar

sensitivity was observed when the beams were re-oriented

in the nominal position geometry. The pass-rate

reductions observed with films showed a more irregular

trend, and the maximum reduction was 16%. The average

pass-rates obtained over clinical plans are shown in fig.2,

for the three gamma index criteria. The mean values

obtained by the 1000 SRS array, using both the clinical and

nominal beam geometry, and by film-dosimetry are all

above 92%, when using 3%, 1mm criteria. Differences

among the mean pass-rates observed for the three

measurement modalities were not statistically significant

(p> 0.1, t-test)

Conclusion

The results confirm that the 1000SRS array is reliable for

pre-treatment QA of CyberKnife MLC plans. The test

scenarios highlighted a higher sensitivity to small leaves

shifts than what observed by film dosimetry. The gamma

pass-rates obtained for clinical plans DQA were

comparable to film pass-rates. The possibility to use the

beam nominal position was validated and can be an

alternative to eliminate SDD and angle dependence.

EP-1484 Validation of ptw’s diamond as alternative

method for the imrt-vmat pretreatment verification

A. Niebla Piñero

1

, B.C. Portas Ferradás

1

, P. Rosa

Menéndez

1

, J.A. Merino Gestoso

1

, M. Rodríguez Pazos

1

, D.

Pardo Calvo

1

, B. Sobral Aspérez

1

1

Hospital Universitario Nuestra Señora de Candelaria,

Medical Physics, Santa Cruz de Tenerife, Spain

Purpose or Objective

The aim of the study is the validation of the software

DIAMOND, as alternative method to ion chamber point

dose measurements to verify prostate’s IMRT-VMAT plans.

For this purpose, we have selected 109 IMRT and 65 VMAT

treated plans between the 12/09/2013 to 08/16/2016. We

have compared the results using Diamond with the ion

chamber results in the pretreatment verification. Using a

ROC analysis we have obtained the new tolerances to

apply in our QA program.

Material and Methods

We have selected 109 IMRT step & shoot plans calculated

with CMS XiO and 65 VMAT calculated with CMS MONACO.

This plans were calculated over the own patient’s CT and

also over the I’mRT phantom’s CT used for the point dose

verification. These plans were sent to DIAMOND to make

the recalculation in two points: One of them in a high

dose-low gradient region (P1), and the other in a high