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Action limits - Proposed philosophy

Step 4:

Define the center of the true dose probability distribution

as the lower and upper

action limit

, respectively.

Prescribed dose

Dose (Gy)

Probability distribution

for the true dose

−∆

TL

+∆

TL

Clinical tolerance

limits

is set to a minimum

acceptable cure rate

is set to a maximum

acceptable complication rate

From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)