Step 3:
Adjust the
true dose probability distribution
such that the dose
limits
IDC-C
α
/2
and
IDC+C
α
/2
coincide with the
clinical tolerance
limits.
Prescribed dose
Action limits - Proposed philosophy
Dose (Gy)
Probability distribution
for the true dose
−∆
TL
+∆
TL
T.
From JörgenOlofsson (Dose Modeling and dose verification ESTRO COURSE)
Prague 2013
Clinical tolerance
limits
is set to a minimum
acceptable cure rate
is set to a maximum
acceptable complication rate