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Step 4:
Define the center of the true dose probability distribution
as the lower and upper
action limit
, respectively.
Prescribed dose
Action limits - Proposed philosophy
Dose (Gy)
Probability distribution
for the true dose
−∆
TL
+∆
TL
Clinical tolerance
limits
is set to a minimum
acceptable cure rate
is set to a maximum
acceptable complication rate
From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)